Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin‐deficient and mdx mice

BACKGROUND: Muscular dystrophy (MD) causes muscle wasting and is often lethal in patients due to a lack of proven therapies. In contrast, mouse models of MD are notoriously mild. We have previously shown severe human‐like muscle pathology in mdx [Duchenne MD (DMD)] and dysferlin‐deficient limb‐girdl...

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Detalles Bibliográficos
Autores principales: White, Zoe, Theret, Marine, Milad, Nadia, Tung, Lin Wei, Chen, William Wei‐Han, Sirois, Martin G., Rossi, Fabio, Bernatchez, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles: Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818667/
https://www.ncbi.nlm.nih.gov/pubmed/34927367
http://dx.doi.org/10.1002/jcsm.12879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818667/
https://www.ncbi.nlm.nih.gov/pubmed/34927367
http://dx.doi.org/10.1002/jcsm.12879

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