Cargando…

Everolimus Alleviates Renal Allograft Interstitial Fibrosis by Inhibiting Epithelial-to-Mesenchymal Transition Not Only via Inducing Autophagy but Also via Stabilizing IκB-α

Chronic allograft dysfunction (CAD) is the major cause of late graft loss in long-term renal transplantation. In our previous study, we found that epithelial–mesenchymal transition (EMT) is a significant event in the progression of renal allograft tubulointerstitial fibrosis, and impaired autophagic...

Descripción completa

Detalles Bibliográficos
Autores principales: Gui, Zeping, Suo, Chuanjian, Tao, Jun, Wang, Zijie, Zheng, Ming, Fei, Shuang, Chen, Hao, Sun, Li, Han, Zhijian, Ju, Xiaobing, Zhang, Hengcheng, Gu, Min, Tan, Ruoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818677/
https://www.ncbi.nlm.nih.gov/pubmed/35140705
http://dx.doi.org/10.3389/fimmu.2021.753412