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The Prognostic Value of FoxP3+ Tumour-Infiltrating Lymphocytes in Rectal Cancer Depends on Immune Phenotypes Defined by CD8+ Cytotoxic T Cell Density

Tumour-infiltrating FoxP3+ regulatory T cells have been identified as both positive and negative prognostic factors in colorectal cancer (CRC) and rectal cancer (RC). In this study we investigated whether immune phenotypes, defined by CD8+ cytotoxic T cell density, may influence the prognostic assoc...

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Detalles Bibliográficos
Autores principales: Schnellhardt, Sören, Hirneth, Johannes, Büttner-Herold, Maike, Daniel, Christoph, Haderlein, Marlen, Hartmann, Arndt, Fietkau, Rainer, Distel, Luitpold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818710/
https://www.ncbi.nlm.nih.gov/pubmed/35140715
http://dx.doi.org/10.3389/fimmu.2022.781222