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Demystifying the Relationship Between Metformin, AMPK, and Doxorubicin Cardiotoxicity

Doxorubicin (DOX) is an extremely effective and wide-spectrum anticancer drug, but its long-term use can lead to heart failure, which presents a serious problem to millions of cancer survivors who have been treated with DOX. Thus, identifying agents that can reduce DOX cardiotoxicity and concurrentl...

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Detalles Bibliográficos
Autores principales: Singh, Manrose, Nicol, Akito T., DelPozzo, Jaclyn, Wei, Jia, Singh, Mandeep, Nguyen, Tony, Kobayashi, Satoru, Liang, Qiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818847/
https://www.ncbi.nlm.nih.gov/pubmed/35141304
http://dx.doi.org/10.3389/fcvm.2022.839644