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Demystifying the Relationship Between Metformin, AMPK, and Doxorubicin Cardiotoxicity
Doxorubicin (DOX) is an extremely effective and wide-spectrum anticancer drug, but its long-term use can lead to heart failure, which presents a serious problem to millions of cancer survivors who have been treated with DOX. Thus, identifying agents that can reduce DOX cardiotoxicity and concurrentl...
Autores principales: | Singh, Manrose, Nicol, Akito T., DelPozzo, Jaclyn, Wei, Jia, Singh, Mandeep, Nguyen, Tony, Kobayashi, Satoru, Liang, Qiangrong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818847/ https://www.ncbi.nlm.nih.gov/pubmed/35141304 http://dx.doi.org/10.3389/fcvm.2022.839644 |
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