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Shionone Attenuates Sepsis-Induced Acute Kidney Injury by Regulating Macrophage Polarization via the ECM1/STAT5 Pathway

BACKGROUNDS: To date, there are no specific drugs approved for the treatment of sepsis associated acute kidney injury (AKI). Shionone is a natural component with anti-inflammatory activity. In this study, we sought to determine the functional role of Shionone in sepsis-induced AKI. METHODS: Animal m...

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Detalles Bibliográficos
Autores principales: Zhang, Biao, Xue, Yi, Zhao, Jin, Jiang, Huojun, Zhu, Jiaoli, Yin, Hao, Qiu, Yizhen, Hu, Aihao, Xu, Lingqi, Song, Yi, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818860/
https://www.ncbi.nlm.nih.gov/pubmed/35141243
http://dx.doi.org/10.3389/fmed.2021.796743