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Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats

Simvastatin is an established anti-hyperlipidemic drug and few studies have indicated its role in the mitigation of oxidative stress. However, a systematic study considering molecular binding/interaction of simvastatin with anti-oxidant enzymes followed by confirmational in vitro and in vivo studies...

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Detalles Bibliográficos
Autores principales: Verma, Kanika, Makwana, Shikha, Paliwal, Sarvesh, Paliwal, Vartika, Jain, Smita, Paliwal, Swati, Sharma, Swapnil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818901/
https://www.ncbi.nlm.nih.gov/pubmed/35146420
http://dx.doi.org/10.1016/j.crphar.2022.100088