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Simvastatin ameliorates oxidative stress levels in HepG2 cells and hyperlipidemic rats
Simvastatin is an established anti-hyperlipidemic drug and few studies have indicated its role in the mitigation of oxidative stress. However, a systematic study considering molecular binding/interaction of simvastatin with anti-oxidant enzymes followed by confirmational in vitro and in vivo studies...
Autores principales: | Verma, Kanika, Makwana, Shikha, Paliwal, Sarvesh, Paliwal, Vartika, Jain, Smita, Paliwal, Swati, Sharma, Swapnil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818901/ https://www.ncbi.nlm.nih.gov/pubmed/35146420 http://dx.doi.org/10.1016/j.crphar.2022.100088 |
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