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KAT2A Promotes Hepatitis B Virus Transcription and Replication Through Epigenetic Regulation of cccDNA Minichromosome

Hepatitis B virus (HBV) infection remains a major health problem worldwide. Sufficient maintenance of the HBV covalently closed circular DNA (cccDNA), which serves as a template for HBV transcription, is responsible for the failure of antiviral therapies. While accumulating evidence suggests that cc...

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Detalles Bibliográficos
Autores principales: Qin, Yi-Ping, Yu, Hai-Bo, Yuan, Si-Yu, Yang, Zhen, Ren, Fang, Wang, Qing, Li, Fan, Ren, Ji-Hua, Cheng, Sheng-Tao, Zhou, Yu-Jiao, He, Xin, Zhou, Hong-Zhong, Zhang, Yuan, Tan, Ming, Yang, Min-Li, Zhang, Da-Peng, Wen, Xu, Dong, Mei-Ling, Zhang, Hui, Liu, Jing, Li, Zhi-Hong, Chen, Yao, Huang, Ai-Long, Chen, Wei-Xian, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818952/
https://www.ncbi.nlm.nih.gov/pubmed/35140694
http://dx.doi.org/10.3389/fmicb.2021.795388