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Curcumin Inhibits Membrane-Damaging Pore-Forming Function of the β-Barrel Pore-Forming Toxin Vibrio cholerae Cytolysin

Vibrio cholerae cytolysin (VCC) is a β-barrel pore-forming toxin (β-PFT). Upon encountering the target cells, VCC forms heptameric β-barrel pores and permeabilizes the cell membranes. Structure-function mechanisms of VCC have been extensively studied in the past. However, the existence of any natura...

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Detalles Bibliográficos
Autores principales: Singh, Mahendra, Rupesh, N., Pandit, Shashi Bhushan, Chattopadhyay, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818996/
https://www.ncbi.nlm.nih.gov/pubmed/35140698
http://dx.doi.org/10.3389/fmicb.2021.809782