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B-Cell Dysregulation in Idiopathic Nephrotic Syndrome: What We Know and What We Need to Discover

The therapeutic efficacy of B-cell depletion by anti-CD20 treatment in pediatric and, more recently, in adult idiopathic nephrotic syndrome patients suggests a key role of B cells in the pathogenesis of the disease. However, their exact role is still unclear. B cells are able to secrete a large vari...

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Detalles Bibliográficos
Autores principales: Colucci, Manuela, Oniszczuk, Julie, Vivarelli, Marina, Audard, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819007/
https://www.ncbi.nlm.nih.gov/pubmed/35140723
http://dx.doi.org/10.3389/fimmu.2022.823204