Mutant phosphatidate phosphatase Pah1-W637A exhibits altered phosphorylation, membrane association, and enzyme function in yeast

The Saccharomyces cerevisiae PAH1-encoded phosphatidate (PA) phosphatase, which catalyzes the dephosphorylation of PA to produce diacylglycerol, controls the bifurcation of PA into triacylglycerol synthesis and phospholipid synthesis. Pah1 is inactive in the cytosol as a phosphorylated form and beco...

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Detalles Bibliográficos
Autores principales: Park, Yeonhee, Stukey, Geordan J., Jog, Ruta, Kwiatek, Joanna M., Han, Gil-Soo, Carman, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819029/
https://www.ncbi.nlm.nih.gov/pubmed/35026226
http://dx.doi.org/10.1016/j.jbc.2022.101578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819029/
https://www.ncbi.nlm.nih.gov/pubmed/35026226
http://dx.doi.org/10.1016/j.jbc.2022.101578

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