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Peroxisomal β-oxidation stimulates cholesterol biosynthesis in the liver in diabetic mice

Although diabetes normally causes an elevation of cholesterol biosynthesis and induces hypercholesterolemia in animals and human, the mechanism linking diabetes to the dysregulation of cholesterol biosynthesis in the liver is not fully understood. As liver peroxisomal β-oxidation is induced in the d...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Wang, Yaoqing, Yao, Haoya, Deng, Senwen, Gao, Ting, Shang, Lin, Chen, Xiaocui, Cui, Xiaojuan, Zeng, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819034/
https://www.ncbi.nlm.nih.gov/pubmed/35007532
http://dx.doi.org/10.1016/j.jbc.2022.101572