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A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium

Complex diseases such as cancer and diabetes are underpinned by changes in metabolism, specifically by which and how nutrients are catabolized. Substrate utilization can be directly examined by measuring a metabolic endpoint rather than an intermediate (such as a metabolite in the tricarboxylic acid...

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Detalles Bibliográficos
Autores principales: Krycer, James R., Lor, Mary, Fitzsimmons, Rebecca L., Hudson, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819040/
https://www.ncbi.nlm.nih.gov/pubmed/34971704
http://dx.doi.org/10.1016/j.jbc.2021.101547