Cargando…

Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption

The number of man-made chemicals has increased exponentially recently, and exposure to some of them can induce fetal malformations. Because complex and precisely programmed signaling pathways play important roles in developmental processes, their disruption by external chemicals often triggers devel...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanno, Seiya, Okubo, Yusuke, Kageyama, Tatsuto, Yan, Lei, Kitajima, Satoshi, Fukuda, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819105/
https://www.ncbi.nlm.nih.gov/pubmed/35146387
http://dx.doi.org/10.1016/j.isci.2022.103770