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Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption
The number of man-made chemicals has increased exponentially recently, and exposure to some of them can induce fetal malformations. Because complex and precisely programmed signaling pathways play important roles in developmental processes, their disruption by external chemicals often triggers devel...
Autores principales: | Kanno, Seiya, Okubo, Yusuke, Kageyama, Tatsuto, Yan, Lei, Kitajima, Satoshi, Fukuda, Junji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819105/ https://www.ncbi.nlm.nih.gov/pubmed/35146387 http://dx.doi.org/10.1016/j.isci.2022.103770 |
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