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SUMOylation regulates Rb hyperphosphorylation and inactivation in uveal melanoma

Small ubiquitin‐like modifier (SUMO)ylation is one of the posttranslational modifications and is implicated in many tumor types. Modulation of SUMOylation can affect tumor progression, but the underlying mechanisms remain unclear. Here, we show that, for the first time, in uveal melanoma (UM), the m...

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Detalles Bibliográficos
Autores principales: Meng, Fengxi, Yuan, Yiqun, Ren, Hui, Yue, Han, Xu, Binbin, Qian, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819297/
https://www.ncbi.nlm.nih.gov/pubmed/34839558
http://dx.doi.org/10.1111/cas.15223