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Glycosylation of MUC6 by α1,4‐linked N‐acetylglucosamine enhances suppression of pancreatic cancer malignancy

Biomarkers for early diagnosis of pancreatic cancer are greatly needed, as the high fatality of this cancer is in part due to delayed detection. α1,4‐linked N‐acetylglucosamine (αGlcNAc), a unique O‐glycan specific to gastric gland mucus, is biosynthesized by α1,4‐N‐acetylglucosaminyltransferase (α4...

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Detalles Bibliográficos
Autores principales: Yuki, Atsuko, Fujii, Chifumi, Yamanoi, Kazuhiro, Matoba, Hisanori, Harumiya, Satoru, Kawakubo, Masatomo, Nakayama, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819301/
https://www.ncbi.nlm.nih.gov/pubmed/34808019
http://dx.doi.org/10.1111/cas.15209