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External validity in translational biomedicine: understanding the conditions enabling the cause to have an effect
A spectre is haunting biomedical research: It appears that a substantial fraction of published research results cannot be reproduced, while spectacularly successful novel treatments developed in experimental models of disease too often fail in clinical trials. A reproducibility crisis has been procl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819306/ https://www.ncbi.nlm.nih.gov/pubmed/34927359 http://dx.doi.org/10.15252/emmm.202114334 |