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External validity in translational biomedicine: understanding the conditions enabling the cause to have an effect

A spectre is haunting biomedical research: It appears that a substantial fraction of published research results cannot be reproduced, while spectacularly successful novel treatments developed in experimental models of disease too often fail in clinical trials. A reproducibility crisis has been procl...

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Detalles Bibliográficos
Autores principales: Dirnagl, Ulrich, Bannach‐Brown, Alexandra, McCann, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819306/
https://www.ncbi.nlm.nih.gov/pubmed/34927359
http://dx.doi.org/10.15252/emmm.202114334