FZD10‐targeted α‐radioimmunotherapy with (225)Ac‐labeled OTSA101 achieves complete remission in a synovial sarcoma model

Synovial sarcomas are rare tumors arising in adolescents and young adults. The prognosis for advanced disease is poor, with an overall survival of 12‐18 months. Frizzled homolog 10 (FZD10) is overexpressed in most synovial sarcomas, making it a promising therapeutic target. The results of a phase 1...

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Detalles Bibliográficos
Autores principales: Sudo, Hitomi, Tsuji, Atsushi B., Sugyo, Aya, Harada, Yosuke, Nagayama, Satoshi, Katagiri, Toyomasa, Nakamura, Yusuke, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819345/
https://www.ncbi.nlm.nih.gov/pubmed/34935247
http://dx.doi.org/10.1111/cas.15235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819345/
https://www.ncbi.nlm.nih.gov/pubmed/34935247
http://dx.doi.org/10.1111/cas.15235

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