FGFR2 loss sensitizes MYCN‐amplified neuroblastoma CHP134 cells to CHK1 inhibitor–induced apoptosis

Checkpoint kinase 1 (CHK1) plays a key role in genome surveillance and integrity throughout the cell cycle. Selective inhibitors of CHK1 (CHK1i) are undergoing clinical evaluation for various human malignancies, including neuroblastoma. In this study, one CHK1i‐sensitive neuroblastoma cell line, CHP...

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Detalles Bibliográficos
Autores principales: Ando, Kiyohiro, Ohira, Miki, Takada, Ichiro, Cázares‐Ordoñez, Verna, Suenaga, Yusuke, Nagase, Hiroki, Kobayashi, Shinichi, Koshinaga, Tsugumichi, Kamijo, Takehiko, Makishima, Makoto, Wada, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819351/
https://www.ncbi.nlm.nih.gov/pubmed/34807483
http://dx.doi.org/10.1111/cas.15205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819351/
https://www.ncbi.nlm.nih.gov/pubmed/34807483
http://dx.doi.org/10.1111/cas.15205

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