Inhibition of NPC1L1 disrupts adaptive responses of drug‐tolerant persister cells to chemotherapy

Entering a drug‐tolerant persister (DTP) state of cancer cells is a transient self‐adaptive mechanism by which a residual cell subpopulation accelerates tumor progression. Here, we identified the acquisition of a DTP phenotype in multidrug‐resistant (MDR) cancer cells as a tolerance response to rout...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Qin, Siyuan, Chen, Yan, Zhou, Li, Yang, Mei, Tang, Yongquan, Zuo, Jing, Zhang, Jian, Mizokami, Atsushi, Nice, Edouard C, Chen, Hai‐Ning, Huang, Canhua, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819355/
https://www.ncbi.nlm.nih.gov/pubmed/35023619
http://dx.doi.org/10.15252/emmm.202114903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819355/
https://www.ncbi.nlm.nih.gov/pubmed/35023619
http://dx.doi.org/10.15252/emmm.202114903

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