Targeting NECTIN-1 Based on CRISPR/Cas9 System Attenuated the Herpes Simplex Virus Infection in Human Corneal Epithelial Cells In Vitro

PURPOSE: Viral keratitis caused by herpes simplex virus 1 (HSV-1) is a lifelong recurring disease and an unignored cause of blindness worldwide. Current antiviral therapy cannot eliminate the transcriptionally silent HSV-1 in latently infected patients. With the explosive applications of the cluster...

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Detalles Bibliográficos
Autores principales: Li, Yue, Wei, Yuda, Li, Gang, Huang, Shiqian, Xu, Jianjiang, Ding, Qiurong, Hong, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819356/
https://www.ncbi.nlm.nih.gov/pubmed/35119473
http://dx.doi.org/10.1167/tvst.11.2.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819356/
https://www.ncbi.nlm.nih.gov/pubmed/35119473
http://dx.doi.org/10.1167/tvst.11.2.8

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