Redetermination of the structure of 2-amino-8-thia-1,5-di­aza­spiro­[4.5]dec-1-en-5-ium chloride monohydrate

The reaction of β-(thio­morpholin-1-yl)propio­amidoxime with tosyl chloride in CHCl(3) in the presence of DIPEA when heated at 343 K for 8 h afforded the title hydrated salt, C(7)H(14)N(3)S(+)·Cl(−)·H(2)O, in 84% yield. This course of the tosyl­ation reaction differs from the result of tosyl­ation obtained for this substrate at room temperature, when only 2-amino-8-thia-1,5-di­aza­spiro­[4.5]dec-1-ene-5-ammonium tosyl­ate was isolated in 56% yield. The structure of the reaction product was established by physicochemical methods, spectroscopy, and X-ray diffraction. The single-crystal data demonstrated that the previously reported crystal structure of this compound [Kayukova et al. (2021). Chem. J. Kaz, 74, 21–31] had been refined in a wrong space group. In the extended structure, the chloride anions, water mol­ecules and amine groups of the cations form two-periodic hydrogen-bonded networks with the fes topology.