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Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration

PURPOSE: Based on our preview evidence that reduced nuclear content of the transcription factor Myc-associated protein X (MAX) is an early event associated with degeneration of retinal ganglion cells (RGCs), in the present study, our purpose was to test whether the overexpression of human MAX had a...

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Detalles Bibliográficos
Autores principales: Lani-Louzada, Rafael, Marra, Camila, Dias, Mariana Santana, de Araújo, Victor Guedes, Abreu, Carla Andreia, Ribas, Vinícius Toledo, Adesse, Daniel, Allodi, Silvana, Chiodo, Vince, Hauswirth, William, Petrs-Silva, Hilda, Linden, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819487/
https://www.ncbi.nlm.nih.gov/pubmed/35103748
http://dx.doi.org/10.1167/iovs.63.2.5