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Self-Diffusive Properties of the Intrinsically Disordered Protein Histatin 5 and the Impact of Crowding Thereon: A Combined Neutron Spectroscopy and Molecular Dynamics Simulation Study

[Image: see text] Intrinsically disordered proteins (IDPs) are proteins that, in comparison with globular/structured proteins, lack a distinct tertiary structure. Here, we use the model IDP, Histatin 5, for studying its dynamical properties under self-crowding conditions with quasi-elastic neutron s...

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Detalles Bibliográficos
Autores principales: Fagerberg, Eric, Lenton, Samuel, Nylander, Tommy, Seydel, Tilo, Skepö, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819652/
https://www.ncbi.nlm.nih.gov/pubmed/35044776
http://dx.doi.org/10.1021/acs.jpcb.1c08976