An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea

The sodium–hydrogen exchanger isoform 3 (NHE3, SLC9A3) is abundantly expressed in the gastrointestinal tract and is proposed to play essential roles in Na(+) and fluid absorption as well as acid–base homeostasis. Mutations in the SLC9A3 gene can cause congenital sodium diarrhea (CSD). However, under...

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Detalles Bibliográficos
Autores principales: Xue, Jianxiang, Thomas, Linto, Tahmasbi, Maryam, Valdez, Alexandria, Dominguez Rieg, Jessica A., Fenton, Robert A., Rieg, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819665/
https://www.ncbi.nlm.nih.gov/pubmed/32227118
http://dx.doi.org/10.1042/CS20200065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819665/
https://www.ncbi.nlm.nih.gov/pubmed/32227118
http://dx.doi.org/10.1042/CS20200065

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