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An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea
The sodium–hydrogen exchanger isoform 3 (NHE3, SLC9A3) is abundantly expressed in the gastrointestinal tract and is proposed to play essential roles in Na(+) and fluid absorption as well as acid–base homeostasis. Mutations in the SLC9A3 gene can cause congenital sodium diarrhea (CSD). However, under...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819665/ https://www.ncbi.nlm.nih.gov/pubmed/32227118 http://dx.doi.org/10.1042/CS20200065 |