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Single-cell transcriptomics reveals a low CD8(+) T cell infiltrating state mediated by fibroblasts in recurrent renal cell carcinoma

PURPOSE: Recurrent renal cell carcinoma(reRCC) is associated with poor prognosis and the underlying mechanism is not yet clear. A comprehensive understanding of tumor microenvironment (TME) of reRCC may aid in designing effective anticancer therapies, including immunotherapies. Single-cell transcrip...

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Detalles Bibliográficos
Autores principales: Peng, Yu-Lu, Xiong, Long-Bin, Zhou, Zhao-Hui, Ning, Kang, Li, Zhen, Wu, Ze-Shen, Deng, Min-Hua, Wei, Wen-Su, Wang, Ning, Zou, Xiang-Peng, He, Zhi-Song, Huang, Ji-Wei, Luo, Jun-Hang, Liu, Jian-Ye, Jia, Nan, Cao, Yun, Han, Hui, Guo, Sheng-Jie, Dong, Pei, Yu, Chun-Ping, Zhou, Fang-Jian, Zhang, Zhi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819783/
https://www.ncbi.nlm.nih.gov/pubmed/35121646
http://dx.doi.org/10.1136/jitc-2021-004206