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Statistical analysis plan for the OPTIMUM study: optimising immunisation using mixed schedules, an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule

OBJECTIVE: The purpose of this double-blind, randomised, controlled trial is to compare allergic outcomes in children following vaccination with acellular pertussis (aP) antigen (standard of care in Australia) given at 2 months of age versus whole cell pertussis (wP) in the infant vaccine schedule....

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Detalles Bibliográficos
Autores principales: Totterdell, James A., Chacon, Gladymar Perez, Estcourt, Marie J., Jones, Mark, Richmond, Peter, Snelling, Thomas L., Marsh, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819850/
https://www.ncbi.nlm.nih.gov/pubmed/35130946
http://dx.doi.org/10.1186/s13063-021-05874-6