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In silico study of substrate chemistry effect on the tethering of engineered antibodies for SARS-CoV-2 detection: Amorphous silica vs gold

The influence of the properties of different solid substrates on the tethering of two antibodies, IgG1-CR3022 and IgG1-S309, which were specifically engineered for the detection of SARS-CoV-2, has been examined at the molecular level using conventional and accelerated Molecular Dynamics (cMD and aMD...

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Detalles Bibliográficos
Autores principales: Martí, Didac, Martín-Martínez, Eduard, Torras, Juan, Betran, Oscar, Turon, Pau, Alemán, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820101/
https://www.ncbi.nlm.nih.gov/pubmed/35158221
http://dx.doi.org/10.1016/j.colsurfb.2022.112400