The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling

Vascular endothelial cells (ECs) form a critical interface between blood and tissues that maintains whole-body homeostasis. In COVID-19, disruption of the EC barrier results in edema, vascular inflammation, and coagulation, hallmarks of this severe disease. However, the mechanisms by which ECs are d...

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Detalles Bibliográficos
Autores principales: Robles, Juan Pablo, Zamora, Magdalena, Adan-Castro, Elva, Siqueiros-Marquez, Lourdes, Martinez de la Escalera, Gonzalo, Clapp, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820157/
https://www.ncbi.nlm.nih.gov/pubmed/35143839
http://dx.doi.org/10.1016/j.jbc.2022.101695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820157/
https://www.ncbi.nlm.nih.gov/pubmed/35143839
http://dx.doi.org/10.1016/j.jbc.2022.101695

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