Cargando…

Thermodynamic and structural insights into the repurposing of drugs that bind to SARS-CoV-2 main protease

Although researchers have been working tirelessly since the COVID-19 outbreak, so far only three drugs – remdesivir, ronapreve and molnupiravir – have been approved for use in some countries which directly target the SARS-CoV-2 virus. Given the slow pace and substantial costs of new drug discovery a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Shunzhou, Bhati, Agastya P., Wade, Alexander D., Alfè, Dario, Coveney, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820189/
https://www.ncbi.nlm.nih.gov/pubmed/35223088
http://dx.doi.org/10.1039/d1me00124h