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Involvement of TOB1 on autophagy in gastric cancer AGS cells via decreasing the activation of AKT/mTOR signaling pathway

BACKGROUND: We previously identified the tumor suppressor gene TOB1 as related to gastric cancer. The purpose of this study was to explore whether TOB1 induces autophagy through the AKT/mTOR signaling pathway in gastric cancer. METHODS: Western blotting was used to detect the protein levels of TOB1,...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Li, Yunlong, Sui, Shuning, Cai, Mengdi, Dong, Kexian, Wang, Ping, Liang, Xiao, Fu, Songbin, Yu, Jingcui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820212/
https://www.ncbi.nlm.nih.gov/pubmed/35186488
http://dx.doi.org/10.7717/peerj.12904