Proline-specific aminopeptidase P prevents replication-associated genome instability

Genotoxic stress during DNA replication constitutes a serious threat to genome integrity and causes human diseases. Defects at different steps of DNA metabolism are known to induce replication stress, but the contribution of other aspects of cellular metabolism is less understood. We show that amino...

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Detalles Bibliográficos
Autores principales: Silva, Nicola, Castellano-Pozo, Maikel, Matsuzaki, Kenichiro, Barroso, Consuelo, Roman-Trufero, Monica, Craig, Hannah, Brooks, Darren R., Isaac, R. Elwyn, Boulton, Simon J., Martinez-Perez, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820600/
https://www.ncbi.nlm.nih.gov/pubmed/35081133
http://dx.doi.org/10.1371/journal.pgen.1010025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820600/
https://www.ncbi.nlm.nih.gov/pubmed/35081133
http://dx.doi.org/10.1371/journal.pgen.1010025

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