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Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy
Chimeric antigen receptor (CAR) T-cell therapy is potentially an effective targeted immunotherapy for glioblastoma, yet there is presently little known about the efficacy of CAR T-cell treatment when combined with the widely used anti-inflammatory and immunosuppressant glucocorticoid, dexamethasone....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820647/ https://www.ncbi.nlm.nih.gov/pubmed/35081104 http://dx.doi.org/10.1371/journal.pcbi.1009504 |