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Human Cardiac Organoids to Model COVID-19 Cytokine Storm Induced Cardiac Injuries

Acute cardiac injuries occur in 20–25% of hospitalized COVID-19 patients. Despite urgent needs, there is a lack of 3D organotypic models of COVID-19 hearts for mechanistic studies and drug testing. Herein, we demonstrate that human cardiac organoids (hCOs) are a viable platform to model the cardiac...

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Detalles Bibliográficos
Autores principales: Arhontoulis, Dimitrios C, Kerr, Charles, Richards, Dylan, Tjen, Kelsey, Hyams, Nathaniel, Jones, Jefferey A., Deleon-Pennell, Kristine, Menick, Donald, Lindner, Diana, Westermann, Dirk, Mei, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820666/
https://www.ncbi.nlm.nih.gov/pubmed/35132419
http://dx.doi.org/10.1101/2022.01.31.478497