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A δ-cell subpopulation with a pro-β-cell identity contributes to efficient age-independent recovery in a zebrafish model of diabetes

Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new Insulin-expressing cells. To overcome the weak regenerative capacity of mammals, we used regeneration-prone...

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Detalles Bibliográficos
Autores principales: Carril Pardo, Claudio Andrés, Massoz, Laura, Dupont, Marie A, Bergemann, David, Bourdouxhe, Jordane, Lavergne, Arnaud, Tarifeño-Saldivia, Estefania, Helker, Christian SM, Stainier, Didier YR, Peers, Bernard, Voz, Marianne M, Manfroid, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820734/
https://www.ncbi.nlm.nih.gov/pubmed/35060900
http://dx.doi.org/10.7554/eLife.67576