FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons

Neurons rely on translation of synaptic mRNAs in order to generate activity-dependent changes in plasticity. Here, we develop a strategy combining compartment-specific crosslinking immunoprecipitation (CLIP) and translating ribosome affinity purification (TRAP) in conditionally tagged mice to precis...

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Detalles Bibliográficos
Autores principales: Hale, Caryn R, Sawicka, Kirsty, Mora, Kevin, Fak, John J, Kang, Jin Joo, Cutrim, Paula, Cialowicz, Katarzyna, Carroll, Thomas S, Darnell, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820740/
https://www.ncbi.nlm.nih.gov/pubmed/34939924
http://dx.doi.org/10.7554/eLife.71892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820740/
https://www.ncbi.nlm.nih.gov/pubmed/34939924
http://dx.doi.org/10.7554/eLife.71892

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