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A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon

The extremely high transmission rate of SARS-CoV-2 and severe cases of COVID-19 pose the two critical challenges in the battle against COVID-19. Increasing evidence has shown that the viral spike (S) protein-driven syncytia may be responsible for these two events. Intensive attention has thus been d...

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Detalles Bibliográficos
Autores principales: Li, Na, Chen, Xiao-Ling, Li, Qi, Zhang, Zhe-Rui, Deng, Cheng-Lin, Zhang, Bo, Li, Xiao-Dan, Ye, Han-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820800/
https://www.ncbi.nlm.nih.gov/pubmed/35034586
http://dx.doi.org/10.1080/22221751.2022.2030198