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Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures

INTRODUCTION: Individuals with focal segmental glomerular sclerosis (FSGS) typically undergo kidney biopsy only once, which limits the ability to characterize kidney cell gene expression over time. METHODS: We used single-cell RNA sequencing (scRNA-seq) to explore disease-related molecular signature...

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Detalles Bibliográficos
Autores principales: Latt, Khun Zaw, Heymann, Jurgen, Jessee, Joseph H., Rosenberg, Avi Z., Berthier, Celine C., Arazi, Arnon, Eddy, Sean, Yoshida, Teruhiko, Zhao, Yongmei, Chen, Vicky, Nelson, George W., Cam, Margaret, Kumar, Parimal, Mehta, Monika, Kelly, Michael C., Kretzler, Matthias, Ray, Patricio E., Moxey-Mims, Marva, Gorman, Gregory H., Lechner, Brent L., Regunathan-Shenk, Renu, Raj, Dominic S., Susztak, Katalin, Winkler, Cheryl A., Kopp, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821042/
https://www.ncbi.nlm.nih.gov/pubmed/35155868
http://dx.doi.org/10.1016/j.ekir.2021.11.005