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Evolution of Disease Modifying Therapy Benefits and Risks: An Argument for De-escalation as a Treatment Paradigm for Patients With Multiple Sclerosis

BACKGROUND: Strategies for sequencing disease modifying therapies (DMTs) in multiple sclerosis (MS) patients include escalation, high efficacy early, induction, and de-escalation. OBJECTIVE: To provide a perspective on de-escalation, which aims to match the ratio of DMT benefit/risk in aging patient...

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Detalles Bibliográficos
Autores principales: Vollmer, Brandi L., Wolf, Andrew B., Sillau, Stefan, Corboy, John R., Alvarez, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821102/
https://www.ncbi.nlm.nih.gov/pubmed/35145470
http://dx.doi.org/10.3389/fneur.2021.799138