T Cell Repertoire Abnormality in Immunodeficiency Patients with DNA Repair and Methylation Defects

Both DNA damage response and methylation play a crucial role in antigen receptor recombination by creating a diverse repertoire in developing lymphocytes, but how their defects relate to T cell repertoire and phenotypic heterogeneity of immunodeficiency remains obscure. We studied the TCR repertoire...

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Detalles Bibliográficos
Autores principales: Fang, Mingyan, Su, Zheng, Abolhassani, Hassan, Zhang, Wei, Jiang, Chongyi, Cheng, Bochen, Luo, Lihua, Wu, Jinghua, Wang, Shiyu, Lin, Liya, Wang, Xie, Wang, Longlong, Aghamohammadi, Asghar, Li, Tao, Zhang, Xiuqing, Hammarström, Lennart, Liu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821531/
https://www.ncbi.nlm.nih.gov/pubmed/34825286
http://dx.doi.org/10.1007/s10875-021-01178-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821531/
https://www.ncbi.nlm.nih.gov/pubmed/34825286
http://dx.doi.org/10.1007/s10875-021-01178-1

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