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CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy

High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy due to the lack of reliable biomarkers, effective treatment, and chemoresistance. Improving the diagnosis and the development of targeted therapies is still needed. The molecular pathomechanisms driving HGSC progres...

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Detalles Bibliográficos
Autores principales: Salgado-Albarrán, Marisol, Späth, Julian, González-Barrios, Rodrigo, Baumbach, Jan, Soto-Reyes, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821627/
https://www.ncbi.nlm.nih.gov/pubmed/35132075
http://dx.doi.org/10.1038/s41540-022-00214-z