Presynaptic NMDARs on spinal nociceptor terminals state-dependently modulate synaptic transmission and pain

Postsynaptic NMDARs at spinal synapses are required for postsynaptic long-term potentiation and chronic pain. However, how presynaptic NMDARs (PreNMDARs) in spinal nociceptor terminals control presynaptic plasticity and pain hypersensitivity has remained unclear. Here we report that PreNMDARs in spi...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Rou-Gang, Chu, Wen-Guang, Liu, Da-Lu, Wang, Xu, Ma, Sui-Bin, Wang, Fei, Wang, Fu-Dong, Lin, Zhen, Wu, Wen-Bin, Lu, Na, Liu, Ying-Ying, Han, Wen-Juan, Zhang, Hui, Bai, Zhan-Tao, Hu, San-Jue, Tao, Hui-Ren, Kuner, Thomas, Zhang, Xu, Kuner, Rohini, Wu, Sheng-Xi, Luo, Ceng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821657/
https://www.ncbi.nlm.nih.gov/pubmed/35132099
http://dx.doi.org/10.1038/s41467-022-28429-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821657/
https://www.ncbi.nlm.nih.gov/pubmed/35132099
http://dx.doi.org/10.1038/s41467-022-28429-y

Ejemplares similares