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A Repurposed Drug Screen for Compounds Regulating Aquaporin 5 Stability in Lung Epithelial Cells

Aquaporin 5 (AQP5) is expressed in several cell types in the lung and regulates water transport, which contributes to barrier function during injury and the composition of glandular secretions. Reduced AQP5 expression is associated with barrier dysfunction during acute lung injury, and strategies to...

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Detalles Bibliográficos
Autores principales: Villandre, John, White, Virginia, Lear, Travis B., Chen, Yanwen, Tuncer, Ferhan, Vaiz, Emily, Tuncer, Beyza, Lockwood, Karina, Camarco, Dan, Liu, Yuan, Chen, Bill B., Evankovich, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821664/
https://www.ncbi.nlm.nih.gov/pubmed/35145418
http://dx.doi.org/10.3389/fphar.2022.828643