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Reconstituting the complete biosynthesis of D-lysergic acid in yeast

The ergot alkaloids are a class of natural products known for their pharmacologically privileged molecular structure that are used in the treatment of neurological ailments, such as Parkinsonism and dementia. Their synthesis via chemical and biological routes are therefore of industrial relevance, b...

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Detalles Bibliográficos
Autores principales: Wong, Garrett, Lim, Li Rong, Tan, Yong Quan, Go, Maybelle Kho, Bell, David J., Freemont, Paul S., Yew, Wen Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821704/
https://www.ncbi.nlm.nih.gov/pubmed/35132076
http://dx.doi.org/10.1038/s41467-022-28386-6