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PD-L1(P146R) is prognostic and a negative predictor of response to immunotherapy in gastric cancer

Cancer cells evade immune detection via programmed cell death 1/programmed cell death-ligand 1 (PD-1/PD-L1) interactions that inactivate T cells. PD-1/PD-L1 blockade has become an important therapy in the anti-cancer armamentarium. However, some patients do not benefit from PD-1/PD-L1 blockade despi...

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Detalles Bibliográficos
Autores principales: Li, Qing, Zhou, Zhi-Wei, Lu, Jia, Luo, Hao, Wang, Shu-Nan, Peng, Yu, Deng, Meng-Sheng, Song, Guan-Bin, Wang, Jian-Min, Wei, Xi, Wang, Dong, Westover, Kenneth D., Xu, Cheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8821936/
https://www.ncbi.nlm.nih.gov/pubmed/34547468
http://dx.doi.org/10.1016/j.ymthe.2021.09.013