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Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage

BACKGROUND: Neuroinflammation and blood coagulation responses in cerebrospinal fluid (CSF) contribute to the poor outcome associated with subarachnoid haemorrhage (SAH). We explored the role of caspase-1-mediated inflammasome activation on extrinsic blood coagulation in CSF after SAH. METHODS: Post-...

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Detalles Bibliográficos
Autores principales: Fang, Yuanjian, Wang, Xiaoyu, Lu, Jianan, Shi, Hui, Huang, Lei, Shao, Anwen, Zhang, Anke, Liu, Yibo, Ren, Reng, Lenahan, Cameron, Tang, Jiping, Zhang, Jianmin, Zhang, John H., Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822177/
https://www.ncbi.nlm.nih.gov/pubmed/35101655
http://dx.doi.org/10.1016/j.ebiom.2022.103843