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Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

BACKGROUND: Osteoarthritis (OA) is the most common joint disease and is the leading cause of chronic disability among older people. Chondrocyte death and extracellular matrix (ECM) degradation was involved in OA pathogenesis. Ferroptosis was an iron-dependent cell death associated with peroxidation...

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Detalles Bibliográficos
Autores principales: Miao, Yu, Chen, Yiwei, Xue, Feng, Liu, Kexin, Zhu, Bin, Gao, Junjie, Yin, Junhui, Zhang, Changqing, Li, Guangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8822178/
https://www.ncbi.nlm.nih.gov/pubmed/35101656
http://dx.doi.org/10.1016/j.ebiom.2022.103847